Performance of the 4C and SEIMC scoring systems in predicting mortality from onset to current COVID-19 pandemic in emergency departments

Artículo Materias > Biomedicina Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica
Abierto Inglés The evolution of the COVID-19 pandemic has been associated with variations in clinical presentation and severity. Similarly, prediction scores may suffer changes in their diagnostic accuracy. The aim of this study was to test the 30-day mortality predictive validity of the 4C and SEIMC scores during the sixth wave of the pandemic and to compare them with those of validation studies. This was a longitudinal retrospective observational study. COVID-19 patients who were admitted to the Emergency Department of a Spanish hospital from December 15, 2021, to January 31, 2022, were selected. A side-by-side comparison with the pivotal validation studies was subsequently performed. The main measures were 30-day mortality and the 4C and SEIMC scores. A total of 27,614 patients were considered in the study, including 22,361 from the 4C, 4,627 from the SEIMC and 626 from our hospital. The 30-day mortality rate was significantly lower than that reported in the validation studies. The AUCs were 0.931 (95% CI: 0.90–0.95) for 4C and 0.903 (95% CI: 086–0.93) for SEIMC, which were significantly greater than those obtained in the first wave. Despite the changes that have occurred during the coronavirus disease 2019 (COVID-19) pandemic, with a reduction in lethality, scorecard systems are currently still useful tools for detecting patients with poor disease risk, with better prognostic capacity. metadata de Santos Castro, Pedro Ángel; del Pozo Vegas, Carlos; Pinilla Arribas, Leyre Teresa; Zalama Sánchez, Daniel; Sanz-García, Ancor; Vásquez del Águila, Tony Giancarlo; González Izquierdo, Pablo; de Santos Sánchez, Sara; Mazas Pérez-Oleaga, Cristina; Dominguez Azpíroz, Irma; Elío Pascual, Iñaki y Martín-Rodríguez, Francisco mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, cristina.mazas@uneatlantico.es, irma.dominguez@unini.edu.mx, inaki.elio@uneatlantico.es, SIN ESPECIFICAR (2024) Performance of the 4C and SEIMC scoring systems in predicting mortality from onset to current COVID-19 pandemic in emergency departments. Scientific Reports, 14 (1). ISSN 2045-2322

[img]
Vista Previa
Texto
s41598-024-73664-6.pdf

Descargar (2MB) | Vista Previa

Resumen

The evolution of the COVID-19 pandemic has been associated with variations in clinical presentation and severity. Similarly, prediction scores may suffer changes in their diagnostic accuracy. The aim of this study was to test the 30-day mortality predictive validity of the 4C and SEIMC scores during the sixth wave of the pandemic and to compare them with those of validation studies. This was a longitudinal retrospective observational study. COVID-19 patients who were admitted to the Emergency Department of a Spanish hospital from December 15, 2021, to January 31, 2022, were selected. A side-by-side comparison with the pivotal validation studies was subsequently performed. The main measures were 30-day mortality and the 4C and SEIMC scores. A total of 27,614 patients were considered in the study, including 22,361 from the 4C, 4,627 from the SEIMC and 626 from our hospital. The 30-day mortality rate was significantly lower than that reported in the validation studies. The AUCs were 0.931 (95% CI: 0.90–0.95) for 4C and 0.903 (95% CI: 086–0.93) for SEIMC, which were significantly greater than those obtained in the first wave. Despite the changes that have occurred during the coronavirus disease 2019 (COVID-19) pandemic, with a reduction in lethality, scorecard systems are currently still useful tools for detecting patients with poor disease risk, with better prognostic capacity.

Tipo de Documento: Artículo
Palabras Clave: COVID-19 pandemic, Scoring systems, 4C mortality score, SEIMC score, Mortality, Emergency department
Clasificación temática: Materias > Biomedicina
Divisiones: Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica
Depositado: 08 Oct 2024 23:30
Ultima Modificación: 08 Oct 2024 23:30
URI: https://repositorio.uniromana.edu.do/id/eprint/14584

Acciones (logins necesarios)

Ver Objeto Ver Objeto

<a class="ep_document_link" href="/17844/1/frai-1-1572645.pdf"><img class="ep_doc_icon" alt="[img]" src="/17844/1.hassmallThumbnailVersion/frai-1-1572645.pdf" border="0"/></a>

en

open

A systematic review of deep learning methods for community detection in social networks

Introduction: The rapid expansion of generated data through social networks has introduced significant challenges, which underscores the need for advanced methods to analyze and interpret these complex systems. Deep learning has emerged as an effective approach, offering robust capabilities to process large datasets, and uncover intricate relationships and patterns. Methods: In this systematic literature review, we explore research conducted over the past decade, focusing on the use of deep learning techniques for community detection in social networks. A total of 19 studies were carefully selected from reputable databases, including the ACM Library, Springer Link, Scopus, Science Direct, and IEEE Xplore. This review investigates the employed methodologies, evaluates their effectiveness, and discusses the challenges identified in these works. Results: Our review shows that models like graph neural networks (GNNs), autoencoders, and convolutional neural networks (CNNs) are some of the most commonly used approaches for community detection. It also examines the variety of social networks, datasets, evaluation metrics, and employed frameworks in these studies. Discussion: However, the analysis highlights several challenges, such as scalability, understanding how the models work (interpretability), and the need for solutions that can adapt to different types of networks. These issues stand out as important areas that need further attention and deeper research. This review provides meaningful insights for researchers working in social network analysis. It offers a detailed summary of recent developments, showcases the most impactful deep learning methods, and identifies key challenges that remain to be explored.

Producción Científica

Mohamed El-Moussaoui mail , Mohamed Hanine mail , Ali Kartit mail , Mónica Gracia Villar mail monica.gracia@uneatlantico.es, Helena Garay mail helena.garay@uneatlantico.es, Isabel de la Torre Díez mail ,

El-Moussaoui

<a href="/17825/1/foods-14-02648-v2.pdf" class="ep_document_link"><img class="ep_doc_icon" alt="[img]" src="/17825/1.hassmallThumbnailVersion/foods-14-02648-v2.pdf" border="0"/></a>

en

open

Unhealthy Ultra-Processed Food, Diet Quality and Adherence to the Mediterranean Diet in Children and Adolescents: The DELICIOUS Project

Background: Western dietary patterns worldwide are increasingly dominated by energy-dense, nutrient-deficient industrial foods, often identified as ultra-processed foods (UPFs). Such products may have detrimental health implications, particularly if nutritionally inadequate. This study aimed to examine the intake of unhealthy UPFs among children and adolescents from five Mediterranean countries (Italy, Spain, Portugal, Egypt, and Lebanon) involved in the DELICIOUS project and to assess the association with dietary quality indicators. Methods: A survey was conducted with a sample of 2011 parents of children and adolescents aged 6 to 17 years to evaluate their dietary habits. Diet quality was assessed using the Youth Healthy Eating Index (Y-HEI), the KIDMED index to determine adherence to the Mediterranean diet, and compliance with national dietary guidelines. Results: Increased UPF consumption was not inherently associated with healthy or unhealthy specific food groups, although children and adolescents who consumed UPF daily were less likely to exhibit high overall diet quality and adherence to the Mediterranean diet. In all five countries, greater UPF intake was associated with poorer compliance with dietary recommendations concerning fats, sweets, meat, and legumes. Conclusions: Increased UPF consumption among Mediterranean children and adolescents is associated with an unhealthy dietary pattern, possibly marked by a high intake of fats, sweets, and meat, and a low consumption of legumes.

Producción Científica

Francesca Giampieri mail francesca.giampieri@uneatlantico.es, Alice Rosi mail , Evelyn Frias-Toral mail , Osama Abdelkarim mail , Mohamed Aly mail , Achraf Ammar mail , Raynier Zambrano-Villacres mail , Juancho Pons mail , Laura Vázquez-Araújo mail , Nunzia Decembrino mail , Alessandro Scuderi mail , Alice Leonardi mail , Lorenzo Monasta mail , Fernando Maniega Legarda mail , Ana Mata mail , Adrián Chacón mail , Pablo Busó mail , Giuseppe Grosso mail ,

Giampieri

<a href="/17831/1/s43856-025-01020-4.pdf" class="ep_document_link"><img class="ep_doc_icon" alt="[img]" src="/17831/1.hassmallThumbnailVersion/s43856-025-01020-4.pdf" border="0"/></a>

en

open

Association between blood cortisol levels and numerical rating scale in prehospital pain assessment

Background Nowadays, there is no correlation between levels of cortisol and pain in the prehospital setting. The aim of this work was to determine the ability of prehospital cortisol levels to correlate to pain. Cortisol levels were compared with those of the numerical rating scale (NRS). Methods This is a prospective observational study looking at adult patients with acute disease managed by Emergency Medical Services (EMS) and transferred to the emergency department of two tertiary care hospitals. Epidemiological variables, vital signs, and prehospital blood analysis data were collected. A total of 1516 patients were included, the median age was 67 years (IQR: 51–79; range: 18–103) with 42.7% of females. The primary outcome was pain evaluation by NRS, which was categorized as pain-free (0 points), mild (1–3), moderate (4–6), or severe (≥7). Analysis of variance, correlation, and classification capacity in the form area under the curve of the receiver operating characteristic (AUC) curve were used to prospectively evaluate the association of cortisol with NRS. Results The median NRS and cortisol level are 1 point (IQR: 0–4) and 282 nmol/L (IQR: 143–433). There are 584 pain-free patients (38.5%), 525 mild (34.6%), 244 moderate (16.1%), and 163 severe pain (10.8%). Cortisol levels in each NRS category result in p < 0.001. The correlation coefficient between the cortisol level and NRS is 0.87 (p < 0.001). The AUC of cortisol to classify patients into each NRS category is 0.882 (95% CI: 0.853–0.910), 0.496 (95% CI: 0.446–0.545), 0.837 (95% CI: 0.803–0.872), and 0.981 (95% CI: 0.970–0.991) for the pain-free, mild, moderate, and severe categories, respectively. Conclusions Cortisol levels show similar pain evaluation as NRS, with high-correlation for NRS pain categories, except for mild-pain. Therefore, cortisol evaluation via the EMS could provide information regarding pain status.

Producción Científica

Raúl López-Izquierdo mail , Elisa A. Ingelmo-Astorga mail , Carlos del Pozo Vegas mail , Santos Gracia Villar mail santos.gracia@uneatlantico.es, Luis Alonso Dzul López mail luis.dzul@uneatlantico.es, Silvia Aparicio Obregón mail silvia.aparicio@uneatlantico.es, Rubén Calderón Iglesias mail ruben.calderon@uneatlantico.es, Ancor Sanz-García mail , Francisco Martín-Rodríguez mail ,

López-Izquierdo

<a class="ep_document_link" href="/17838/1/s41598-025-02008-9.pdf"><img class="ep_doc_icon" alt="[img]" src="/17838/1.hassmallThumbnailVersion/s41598-025-02008-9.pdf" border="0"/></a>

en

open

Botnet detection in internet of things using stacked ensemble learning model

Botnets are used for malicious activities such as cyber-attacks, spamming, and data theft and have become a significant threat to cyber security. Despite existing approaches for cyber attack detection, botnets prove to be a particularly difficult problem that calls for more advanced detection methods. In this research, a stacking classifier is proposed based on K-nearest neighbor, support vector machine, decision tree, random forest, and multilayer perceptron, called KSDRM, for botnet detection. Logistic regression acts as the meta-learner to combine the predictions from the base classifiers into the final prediction with the aim of increasing the overall accuracy and predictive performance of the ensemble. The UNSW-NB15 dataset is used to train machine learning models and evaluate their effectiveness in detecting cyber-attacks on IoT networks. The categorical features are transformed into numerical values using label encoding. Machine learning techniques are adopted to recognize botnet attacks to enhance cyber security measures. The KSDRM model successfully captures the complex patterns and traits of botnet attacks and obtains 99.99% training accuracy. The KSDRM model also performs well during testing by achieving an accuracy of 97.94%. Based on 3, 5, 7, and 10 folds, the k-fold cross-validation results show that the proposed method’s average accuracy is 99.89%, 99.88%, 99.89%, and 99.87%, respectively. Further, the demonstration of experiments and results shows the KSDRM model is an effective method to identify botnet-based cyber attacks. The findings of this study have the potential to improve cyber security controls and strengthen networks against changing threats.

Producción Científica

Mudasir Ali mail , Muhammad Faheem Mushtaq mail , Urooj Akram mail , Daniel Gavilanes Aray mail daniel.gavilanes@uneatlantico.es, Manuel Masías Vergara mail manuel.masias@uneatlantico.es, Hanen Karamti mail , Imran Ashraf mail ,

Ali

<a href="/17839/1/s41598-025-05028-7.pdf" class="ep_document_link"><img class="ep_doc_icon" alt="[img]" src="/17839/1.hassmallThumbnailVersion/s41598-025-05028-7.pdf" border="0"/></a>

en

open

Enhanced schizophrenia detection using multichannel EEG and CAOA-RST-based feature selection

Schizophrenia is a mental disorder characterized by hallucinations, delusions, disorganized thinking and behavior, and inappropriate affect. Early and accurate diagnosis of schizophrenia remains a challenge due to the disorder’s complex nature and the limitations of state-of-the-art techniques. It is evident from the literature that electroencephalogram (EEG) signals provide valuable insights into brain activity, but their high dimensionality and complexity pose remain key challenges. Thus, our research introduces a novel approach by integrating the multichannel EGG, Crossover-Boosted Archimedes Optimization Algorithm (CAOA), and Rough Set Theory (RST) for schizophrenia detection. It is a four-stage model. In the first stage, Raw EGG data is collected. The data is passed to the next stage, which is called data preprocessing. This is used for artifact removal, band-pass filtering, and data normalization. The preprocessed data passed to the next stage. In the feature extraction stage, feature selection is performed using CAOA. In addition, classification is performed using a Support Vector Machine (SVM) based on features extracted through Multivariate Empirical Mode Function (MEMF) and entropy measures. The data interpretation stage displays the results to the end user using the data interpretation stage. We experimented and tested our proposed model using real EEG datasets. The simulation results prove that the proposed model achieved an average accuracy of 94.9%, sensitivity of 93.9%, specificity of 96.4%, and precision of 92.7%. Thus, our proposed model demonstrates significant improvements over state-of-the-art methods. In addition, the integration of CAOA and RST effectively addresses the challenges of high-dimensional EEG data, helps optimize the feature selection process, and increases accuracy. In future work, we suggest incorporating large-size datasets that include more diverse patient groups and refining the model with advanced machine-learning models and techniques.

Producción Científica

Mohammad Abrar mail , Abdu Salam mail , Ahmed Albugmi mail , Fahad Al-otaibi mail , Farhan Amin mail , Isabel de la Torre mail , Thania Chio Montero mail , Perla Aracely Arroyo Gala mail ,

Abrar