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Número de documentos: 12.

2025

Artículo Materias > Ingeniería Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica
Cerrado Inglés Icons are the first visual element users encounter when searching for applications in online store. Icons with eye-catching features can make an app stand out in user searches, playing a crucial role in attracting user attention and influencing selection. This increases the likelihood of downloads, which can expand the user base, improve revenue, and enhance engagement, contributing to the application’s overall success. However, the majority of research focused on evaluating appeal of apps through application icons is empirical in nature and may lack comprehensive data analytical approaches. While empirical research holds its significance, it may still be limited by the size of the dataset analyzed and could also be subjective. This proposed research presents a novel data-analytical methodology to analyze a large dataset of application icons from Google Play to determine their influence on downloads. It clusters the icons using three different techniques: -means clustering with two distinct feature vectors and agglomerative clustering, extracting various visual features from the clusters that are strongly correlated with application installs. Subsequently, validation of results has revealed that factors of varied colors, the dominance of white or black colors, text, and exposure in the icons can be linked to downloads. metadata Bilal, Ahmad; Turab Mirza, Hamid; Ahmad, Adnan; Hussain, Ibrar; Raza, Ali; Garay, Helena; Alemany Iturriaga, Josep y Ashraf, Imran mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, helena.garay@uneatlantico.es, josep.alemany@uneatlantico.es, SIN ESPECIFICAR (2025) On the correlation between Google Play Store application icons and downloads. The Computer Journal, 68 (10). pp. 1579-1593. ISSN 0010-4620

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica
Cerrado Inglés Understanding how dietary compounds affect human health is challenged by their molecular complexity and cell-type–specific effects. Conventional multi-cell type (bulk) analyses obscure cellular heterogeneity, while animal and standard in vitro models often fail to replicate human physiology. Single-cell omics technologies—such as single-cell RNA sequencing, as well as single-cell–resolved proteomic and metabolomic approaches—enable high-resolution investigation of nutrient–cell interactions and reveal mechanisms at a single-cell resolution. When combined with advanced human-derived in vitro systems like organoids and organ-on-chip platforms, they support mechanistic studies in physiologically relevant contexts. This review outlines emerging applications of single-cell omics in nutrition research, emphasizing their potential to uncover cell-specific dietary responses, identify nutrient-sensitive pathways, and capture interindividual variability. It also discusses key challenges—including technical limitations, model selection, and institutional biases—and identifies strategic directions to facilitate broader adoption in the field. Collectively, single-cell omics offer a transformative framework to advance human-centric nutrition research. metadata Cassotta, Manuela; Armas Diaz, Yasmany; Cianciosi, Danila; Yang, Bei; Qi, Zexiu; Chen, Ge; Gracia Villar, Santos; Dzul López, Luis Alonso; Grosso, Giuseppe; Quiles, José L.; Xiao, Jianbo; Battino, Maurizio y Giampieri, Francesca mail manucassotta@gmail.com, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, santos.gracia@uneatlantico.es, luis.dzul@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, maurizio.battino@uneatlantico.es, francesca.giampieri@uneatlantico.es (2025) Single-cell omics for nutrition research: an emerging opportunity for human-centric investigations. Critical Reviews in Food Science and Nutrition. pp. 1-15. ISSN 1040-8398

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica
Cerrado Inglés Food security is a universal need worldwide. This study explored the relationship between food security and adherence to the Mediterranean diet in the context of the DELICIOUS project. A survey involving 2,011 parents of children and adolescents aged 6–17 years was conducted. Adherence to the Mediterranean diet was assessed through the KIDMED score. Information regarding the ease of accessing Mediterranean foods, economic allowance, employment and residence was collected. Logistic regressions analyses were performed to test the associations. Individuals living in rural areas and reporting difficulty in obtaining all studied foods were less likely to follow the Mediterranean diet. Higher adherence was associated with a household monthly income higher than €4000. No associations with family status and no differences across countries were found. The progressive shift away from the Mediterranean diet may depend not only on cultural preferences for unhealthier, industrial alternatives but also on family budgets and food accessibility. metadata Scazzina, Francesca; Rosi, Alice; Giampieri, Francesca; Poveda-Loor, Carlos; Abdelkarim, Osama; Aly, Mohamed; Frias-Toral, Evelyn; Pons, Juancho; Vázquez-Araújo, Laura; Sumalla Cano, Sandra; Elío Pascual, Iñaki; Monasta, Lorenzo; Paladino, Nadia; Mata, Ana; Chacón, Adrián; Busó, Pablo y Grosso, Giuseppe mail SIN ESPECIFICAR, SIN ESPECIFICAR, francesca.giampieri@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, sandra.sumalla@uneatlantico.es, inaki.elio@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR (2025) Socio-economic status, food security and adherence to the Mediterranean diet in five Mediterranean countries: the DELICIOUS project. International Journal of Food Sciences and Nutrition, 76 (8). pp. 869-877. ISSN 0963-7486

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica
Cerrado Inglés Strawberries are commonly consumed berries in the Mediterranean area. The fruits present a high concentration of micronutrients and bioactive compounds that confer a plethora of biological activities, including antioxidant and anti-inflammatory properties. This review discusses and updates the recent results of in vivo studies, in animals and humans, focusing on the impact that strawberry consumption has on many common human diseases, such as obesity, cancer, cardiovascular diseases and metabolic disorders; particular attention has been given to the biological effects and molecular mechanisms involved in the beneficial effects exerted by this berry. Evidence suggests these fruits can contribute to preventing or slowing down the progression of many diseases, even though further research is necessary to confirm their long-term effectiveness, to improve patients’ quality of life or prognosis. metadata Cianciosi, Danila; Armas Diaz, Yasmany; Qi, Zexiu; Yang, Bei; Chen, Ge; Cassotta, Manuela; Gracia Villar, Santos; Dzul López, Luis Alonso; Rivas Garcia, Lorenzo; Forbes Hernandez, Tamara Yuliet; Zhang, Di; Mazzoni, Luca; Mezzetti, Bruno; Battino, Maurizio y Giampieri, Francesca mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, manucassotta@gmail.com, santos.gracia@uneatlantico.es, luis.dzul@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, maurizio.battino@uneatlantico.es, francesca.giampieri@uneatlantico.es (2025) Strawberry as a health promoter: an evidence-based review. Where are we 10 years later? Food & Function, 16 (14). pp. 5705-5732. ISSN 2042-6496

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica
Cerrado Inglés Strawberries are commonly consumed berries in the Mediterranean area. The fruits present a high concentration of micronutrients and bioactive compounds that confer a plethora of biological activities, including antioxidant and anti-inflammatory properties. This review discusses and updates the recent results of in vivo studies, in animals and humans, focusing on the impact that strawberry consumption has on many common human diseases, such as obesity, cancer, cardiovascular diseases and metabolic disorders; particular attention has been given to the biological effects and molecular mechanisms involved in the beneficial effects exerted by this berry. Evidence suggests these fruits can contribute to preventing or slowing down the progression of many diseases, even though further research is necessary to confirm their long-term effectiveness, to improve patients’ quality of life or prognosis. metadata Cianciosi, Danila; Armas Diaz, Yasmany; Qi, Zexiu; Yang, Bei; Chen, Ge; Cassotta, Manuela; Gracia Villar, Santos; Dzul López, Luis Alonso; Rivas Garcia, Lorenzo; Forbes Hernandez, Tamara Yuliet; Zhang, Di; Mazzoni, Luca; Mezzetti, Bruno; Battino, Maurizio y Giampieri, Francesca mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, manucassotta@gmail.com, santos.gracia@uneatlantico.es, luis.dzul@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, maurizio.battino@uneatlantico.es, francesca.giampieri@uneatlantico.es (2025) Strawberry as a health promoter: an evidence-based review. Where are we 10 years later? Food & Function, 16 (14). pp. 5705-5732. ISSN 2042-6496

2024

Artículo Materias > Ingeniería Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica
Cerrado Inglés The correct analysis of medical images requires the medical knowledge and expertise of radiologists to understand, clarify, and explain complex patterns and diagnose diseases. After analyzing, radiologists write detailed and well-structured reports that contribute to the precise and timely diagnosis of patients. However, manually writing reports is often expensive and time-consuming, and it is difficult for radiologists to analyze medical images, particularly images with multiple views and perceptions. It is challenging to accurately diagnose diseases, and many methods are proposed to help radiologists, both traditional and deep learning-based. Automatic report generation is widely used to tackle this issue as it streamlines the process and lessens the burden of manual labeling of images. This paper introduces a systematic literature review with a focus on analyses and evaluating existing research on medical report generation. This SLR follows a proper protocol for the planning, reviewing, and reporting of the results. This review recognizes that the most commonly used deep learning models are encoder-decoder frameworks (45 articles), which provide an accuracy of around 92–95%. Transformers-based models (20 articles) are the second most established method and achieve an accuracy of around 91%. The remaining articles explored in this SLR are attention mechanisms (10), RNN-LSTM (10), Large language models (LLM-10), and graph-based methods (4) with promising results. However, these methods also face certain limitations such as overfitting, risk of bias, and high data dependency that impact their performance. The review not only highlights the strengths and challenges of these methods but also suggests ways to handle them in the future to increase the accuracy and timely generation of medical reports. The goal of this review is to direct radiologists toward methods that lessen their workload and provide precise medical diagnoses. metadata Rehman, Marwareed; Shafi, Imran; Ahmad, Jamil; Osorio García, Carlos Manuel; Pascual Barrera, Alina Eugenia y Ashraf, Imran mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, carlos.osorio@uneatlantico.es, alina.pascual@unini.edu.mx, SIN ESPECIFICAR (2024) Advancement in medical report generation: current practices, challenges, and future directions. Medical & Biological Engineering & Computing. ISSN 0140-0118

Artículo Materias > Biomedicina
Materias > Ingeniería
Universidad Europea del Atlántico > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Universidad de La Romana > Investigación > Producción Científica
Cerrado Inglés Leukemia is a type of blood cell cancer that is in the bone marrow’s blood-forming cells. Two types of Leukemia are acute and chronic; acute enhances fast and chronic growth gradually which are further classified into lymphocytic and myeloid leukemias. This work evaluates a unique deep convolutional neural network (CNN) classifier that improves identification precision by carefully examining concatenated peptide patterns. The study uses leukemia protein expression for experiments supporting two different techniques including independence and applied cross-validation. In addition to CNN, multilayer perceptron (MLP), gated recurrent unit (GRU), and recurrent neural network (RNN) are applied. The experimental results show that the CNN model surpasses competitors with its outstanding predictability in independent and cross-validation testing applied on different features extracted from protein expressions such as amino acid composition (AAC) with a group of AAC (GAAC), tripeptide composition (TPC) with a group of TPC (GTPC), and dipeptide composition (DPC) for calculating its accuracies with their receiver operating characteristic (ROC) curve. In independence testing, a feature expression of AAC and a group of GAAC are applied using MLP and CNN modules, and ROC curves are achieved with overall 100% accuracy for the detection of protein patterns. In cross-validation testing, a feature expression on a group of AAC and GAAC patterns achieved 98.33% accuracy which is the highest for the CNN module. Furthermore, ROC curves show a 0.965% extraordinary result for the GRU module. The findings show that the CNN model is excellent at figuring out leukemia illnesses from protein expressions with higher accuracy. metadata Khawaja, Seher Ansar; Farooq, Muhammad Shoaib; Ishaq, Kashif; Alsubaie, Najah; Karamti, Hanen; Caro Montero, Elizabeth; Silva Alvarado, Eduardo René y Ashraf, Imran mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, elizabeth.caro@uneatlantico.es, eduardo.silva@funiber.org, SIN ESPECIFICAR (2024) Prediction of leukemia peptides using convolutional neural network and protein compositions. BMC Cancer, 24 (1). ISSN 1471-2407

2023

Otro Materias > Ciencias Sociales Universidad Europea del Atlántico > Investigación > Herramientas TIC
Fundación Universitaria Internacional de Colombia > Investigación > Herramientas TIC
Universidad Internacional Iberoamericana México > Investigación > Herramientas TIC
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Herramientas TIC
Universidad Internacional do Cuanza > Investigación > Herramientas TIC
Universidad de La Romana > Investigación > Herramientas TIC
Cerrado Inglés, Español A partir de los datos introducidos y de diferentes escenarios, la herramienta del simulador digital genera distintos retos a los estudiantes-emprendedores para poner a prueba y evaluar la parte financiera de una propuesta de emprendimiento y también ofrece recomendaciones en función de la aportación real de diferentes agentes financieros como bancos, inversores privados, business angels o plataformas de financiación colaborativa. metadata SIN ESPECIFICAR mail SIN ESPECIFICAR (2023) Digital Simulator for Entrepreneurial Finance (FINANCEn_LAB). Repositorio de la Universidad.

2019

Otro Materias > Ingeniería Universidad Europea del Atlántico > Investigación > Herramientas TIC
Fundación Universitaria Internacional de Colombia > Investigación > Herramientas TIC
Universidad Internacional Iberoamericana México > Investigación > Herramientas TIC
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Herramientas TIC
Universidad Internacional do Cuanza > Investigación > Herramientas TIC
Universidad de La Romana > Investigación > Herramientas TIC
Cerrado Español El ahogamiento es una de las principales causas de muerte en el mundo, alrededor de 372.000 personas al año, siendo una cifra que se considera subestimada (OMS, 2014). En consecuencia, existe la necesidad de mejorar esta situación considerada de salud pública. El objetivo del proyecto SOSeas es el desarrollo de una herramienta de evaluación para predecir el riesgo dinámico de los ahogamientos en las playas. En los espacios acuáticos recreativos se espera que una herramienta informática pueda mejorar la gestión de la seguridad por parte de los socorristas y también la información de riesgo de ahogamiento para los bañistas. Este proyecto es una continuidad del trabajo realizado en PreventSOS. En aquel caso el foco era el desarrollo de un sistema experto para la identificación, análisis y gestión del riesgo en espacios acuáticos y el diseño de una aplicación web para el registro de incidentes y accidentes. SOSeas pretende mejorar el servicio anterior integrando el sistema de información que provee el Copernicus Marine Environment Monitoring Service (CMEMS) en todo el mundo. Se pretende conseguir suficientes datos para poder nutrir a un sistema basado en técnicas de aprendizaje-máquina. La herramienta SOSeas se desarrolla para dos tipos de usuarios : gestores de playas/socorristas y usuarios recreativos (nadadores, navegantes, surfistas...). Estos usuarios podrán acceder a las condiciones meteorológicas y oceanográficas así como a información a medida sobre las amenazas de estos entornos siempre cambiantes. metadata SIN ESPECIFICAR mail SIN ESPECIFICAR (2019) SOSeas: An assessment tool for predicting the dynamic risk of drowning on beaches. Repositorio de la Universidad. (Inédito)

2016

Otro Materias > Ingeniería Universidad Europea del Atlántico > Investigación > Herramientas TIC
Fundación Universitaria Internacional de Colombia > Investigación > Herramientas TIC
Universidad Internacional Iberoamericana México > Investigación > Herramientas TIC
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Herramientas TIC
Universidad Internacional do Cuanza > Investigación > Herramientas TIC
Universidad de La Romana > Investigación > Herramientas TIC
Cerrado Español Como resultado del proyecto “Nuevos mecanismos para conocer el riesgo de lesión en el deporte en diferentes tramos de la temporada deportiva” se ha generado una herramienta digital que permite llevar el control de las lesiones de cada deportista, así como sus constantes biomecánicas, hábitos de alimentación y estado de salud emocional de tal forma que, se cuenta con información que combina varios factores a un nivel de detalle importante y de modo personalizado para cada jugador. De este modo, se obtienen los inputs para generar el análisis estadístico que alerta sobre las probabilidades de sufrir determinada lesión. Objetivo del Proyecto: Desarrollar una herramienta que permita identificar el riesgo de lesión de un deportista, independientemente del nivel o categoría del mismo, y poder actuar en consecuencia de manera individualizada, según el período de la temporada en el que se encuentre. Financiación: Este proyecto ha sido cofinanciado por la Sociedad de Desarrollo Regional de Cantabria (SODERCAN) y el el Programa Operativo FEDER de Cantabria en el marco del programa denominado I+C= +C 2016 (Investigación + Conocimiento= +Cantabria) que tiene por objetivo el fortalecimiento del tejido industrial de la región. Inicio: 15/12/2016 Fin: 14/12/2018 Código Externo: ID16-IN-022 metadata SIN ESPECIFICAR mail SIN ESPECIFICAR (2016) Nuevos mecanismos para conocer el riesgo de lesión en el deporte en diferentes tramos de la temporada deportiva. R&P (Recovery and Performance). Repositorio de la Universidad. (Inédito)

Otro Materias > Ingeniería Universidad Europea del Atlántico > Investigación > Herramientas TIC
Fundación Universitaria Internacional de Colombia > Investigación > Herramientas TIC
Universidad Internacional Iberoamericana México > Investigación > Herramientas TIC
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Herramientas TIC
Universidad Internacional do Cuanza > Investigación > Herramientas TIC
Universidad de La Romana > Investigación > Herramientas TIC
Cerrado Español El proyecto se centra en el desarrollo de tecnologías para la identificación de riesgos en espacios acuáticos naturales. A partir del conocimiento que se pretende generar, la entidad espera comercializar servicios de soporte para la gestión de riesgos, la acción preventiva y comunicación de emergencias. La propuesta se orienta a crear un sistema experto en la gestión de riesgos en espacios acuáticos naturales (playas), basado por un lado en una aplicación para la evaluación de riesgos, y por otro, en un sistema de registro y análisis de sucesos y accidentes. Esta herramienta debe permitir a los responsables de la gestión de la seguridad en zonas de baño una gestión adecuada y eficaz de los recursos preventivos para minimizar la probabilidad y severidad de riesgos que puedan afectar a la integridad física o a la salud de las personas, y en consecuencia, el aumento de la seguridad acuática en las costas. Objetivo del Proyecto: Desarrollar tecnologías para la identificación de riesgos en espacios acuáticos naturales con el objeto de prevenir ahogamientos y otros incidentes en zonas de playa. Financiación: Este proyecto ha sido cofinanciado por la Sociedad de Desarrollo Regional de Cantabria (SODERCAN) y el el Programa Operativo FEDER de Cantabria en el marco del programa denominado I+C= +C 2016 (Investigación + Conocimiento= +Cantabria) que tiene por objetivo el fortalecimiento del tejido industrial de la región. Inicio: 09/12/2016 Fin: 08/12/2018 Código Externo: ID16-IN-038 metadata SIN ESPECIFICAR mail SIN ESPECIFICAR (2016) PREVENT-SOS: Desarrollo de tecnologías para la identificación de riesgos en espacios acuáticos naturales. Repositorio de la Universidad. (Inédito)

Otro Materias > Ingeniería
Materias > Educación
Universidad Europea del Atlántico > Investigación > Herramientas TIC
Fundación Universitaria Internacional de Colombia > Investigación > Herramientas TIC
Universidad Internacional Iberoamericana México > Investigación > Herramientas TIC
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Herramientas TIC
Universidad Internacional do Cuanza > Investigación > Herramientas TIC
Universidad de La Romana > Investigación > Herramientas TIC
Cerrado Español A pesar del gran incremento de la práctica deportiva en la sociedad occidental en los últimos años, aún hay, según fuentes de la UE, aproximadamente un 50% de la población europea que no hace ejercicio regularmente, lo que está generando un grave problema de salud, especialmente preocupante en la población infantil y juvenil. Del 50% de la población que hace deporte de forma regular, un porcentaje muy alto lo hace solo, en casa o en lugares abiertos públicos sin ninguna supervisión o control por parte de personal especializado, lo que conlleva un cierto riesgo de sufrir lesiones y/o patologías de diferente pronósticos. Ante esta situación compleja de tener la necesidad de promover la actividad física pero intentando aminorar el riesgo de la propia práctica, se propone el desarrollo de una aplicación móvil “freemium” que fomente el ejercicio y que integre una serie de tecnologías innovadoras para incorporar inteligencia artificial que aplicará sobre unos elementos de alerta que puedan generar avisos y geolocalizar al practicante de una forma rápida y eficaz. Entendemos que el desarrollo de este tipo de negocios de carácter tecnológico y de alto grado de responsabilidad social hacia la ciudadanía incrementará el tejido empresarial de Cantabria y generará nuevos puestos de trabajo estables y de alto nivel de formación. Las sinergias que se proponen con instituciones universitarias y de investigación fomentarán los ecosistemas profesionales relacionados con las nuevas tecnologías de la información, la salud y la seguridad. El objetivo de este sistema complejo que se propone es promover la actividad física segura de forma global. metadata SIN ESPECIFICAR mail SIN ESPECIFICAR (2016) SMART ACTIVE LIFE: Desarrollo de tecnologías inteligentes para la promoción de la vida activa y segura. Repositorio de la Universidad. (Inédito)

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Benchmarking multiple instance learning architectures from patches to pathology for prostate cancer detection and grading using attention-based weak supervision

Histopathological evaluation is necessary for the diagnosis and grading of prostate cancer, which is still one of the most common cancers in men globally. Traditional evaluation is time-consuming, prone to inter-observer variability, and challenging to scale. The clinical usefulness of current AI systems is limited by the need for comprehensive pixel-level annotations. The objective of this research is to develop and evaluate a large-scale benchmarking study on a weakly supervised deep learning framework that minimizes the need for annotation and ensures interpretability for automated prostate cancer diagnosis and International Society of Urological Pathology (ISUP) grading using whole slide images (WSIs). This study rigorously tested six cutting-edge multiple instance learning (MIL) architectures (CLAM-MB, CLAM-SB, ILRA-MIL, AC-MIL, AMD-MIL, WiKG-MIL), three feature encoders (ResNet50, CTransPath, UNI2), and four patch extraction techniques (varying sizes and overlap) using the PANDA dataset (10,616 WSIs), yielding 72 experimental configurations. The methodology used distributed cloud computing to process over 31 million tissue patches, implementing advanced attention mechanisms to ensure clinical interpretability through Grad-CAM visualizations. The optimum configuration (UNI2 encoder with ILRA-MIL, 256 256 patches, 50% overlap) achieved 78.75% accuracy and 90.12% quadratic weighted kappa (QWK), outperforming traditional methods and approaching expert pathologist-level diagnostic capability. Overlapping smaller patches offered the best balance of spatial resolution and contextual information, while domain-specific foundation models performed noticeably better than generic encoders. This work is the first large-scale, comprehensive comparison of weekly supervised MIL methods for prostate cancer diagnosis and grading. The proposed approach has excellent clinical diagnostic performance, scalability, practical feasibility through cloud computing, and interpretability using visualization tools.

Producción Científica

Naveed Anwer Butt mail , Dilawaiz Sarwat mail , Irene Delgado Noya mail irene.delgado@uneatlantico.es, Kilian Tutusaus mail kilian.tutusaus@uneatlantico.es, Nagwan Abdel Samee mail , Imran Ashraf mail ,

Butt

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A Systematic Literature Review on Integrated Deep Learning and Multi-Agent Vision-Language Frameworks for Pathology Image Analysis and Report Generation

This systematic literature review (SLR) investigates the integration of deep learning (DL), vision-language models(VLMs), and multi-agent systems in the analysis of pathology images and automated report generation. The rapidadvancement of whole-slide imaging (WSI) technologies has posed new challenges in pathology, especially due to thescale and complexity of the data. DL techniques in general and convolutional neural networks (CNNs) and transform-ers in particular have significantly enhanced image analysis tasks including segmentation, classification, and detection.However, these models often lack generalizability to generate coherent, clinically relevant text, thus necessitating theintegration of VLMs and large language models (LLMs). This review examines the effectiveness of VLMs and LLMsin bridging the gap between visual data and clinical text, focusing on their potential for automating the generationof pathology reports. Additionally, multi-agent systems, which leverage specialized artificial intelligence (AI) agentsto collaboratively perform diagnostic tasks, are explored for their contributions to improving diagnostic accuracy andscalability. Through a synthesis of recent studies, this review highlights the successes, challenges, and future direc-tions of these AI technologies in pathology diagnostics, offering a comprehensive foundation for the development ofintegrated, AI-driven diagnostic workflows.

Producción Científica

Usama Ali mail , Imran Shafi mail , Jamil Ahmad mail , Arlette Zárate Cáceres mail , Thania Chio Montero mail , Hafiz Muhammad Raza ur Rehman mail , Imran Ashraf mail ,

Ali

<a href="/27552/1/fnut-13-1744444.pdf" class="ep_document_link"><img class="ep_doc_icon" alt="[img]" src="/27552/1.hassmallThumbnailVersion/fnut-13-1744444.pdf" border="0"/></a>

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Inflammatory potential of the diet and self-rated quality of life in Italian adults

Background: Dietary quality is widely acknowledged as a key factor in maintaining good health. Recommendations that promote plant-based eating patterns are largely grounded in evidence showing that dietary choices can modulate the immune function. In line with such a hypothesis, diet may be considered as a potential driver of persistent low-grade inflammation. Quality of life (QoL), on the other hand, serves as a broad indicator that encompasses both physical and psychological wellbeing.Aim: The purpose of this cross-sectional study was to examine the relationship between the inflammatory potential of the diet and QoL in a population sample of Italian adults.Design: A total of 1,936 participants completed a 110-item food frequency questionnaire to assess eating habits. The inflammatory potential of their diet was calculated using the dietary inflammatory score (DIS). Quality of life was measured with the Manchester Short Appraisal (MANSA).Results: Higher DIS values, reflecting a more pro-inflammatory diet, were linked to reduced likelihood of reporting high QoL (OR = 0.56; 95% CI: 0.40–0.78). Several specific domains of QoL, including general life satisfaction, social relationships, personal safety, satisfaction with cohabitation, physical health, and mental health, also showed significant associations with DIS.Conclusion: The findings suggest an association between the inflammatory potential of the diet and QoL.

Producción Científica

Francesca Giampieri mail francesca.giampieri@uneatlantico.es, Justyna Godos mail , Giuseppe Caruso mail , Marco Antonio Olvera-Moreira mail , Fabrizio Furnari mail , Andrea Di Mauro mail , Irma Dominguez Azpíroz mail irma.dominguez@unini.edu.mx, Raynier Zambrano-Villacres mail , Evelyn Frias-Toral mail , Fabio Galvano mail , Giuseppe Grosso mail ,

Giampieri

<a href="/27968/1/sensors-26-01516-v2.pdf" class="ep_document_link"><img class="ep_doc_icon" alt="[img]" src="/27968/1.hassmallThumbnailVersion/sensors-26-01516-v2.pdf" border="0"/></a>

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Human Activity Recognition in Domestic Settings Based on Optical Techniques and Ensemble Models

Human activity recognition (HAR) is essential in many applications, such as smart homes, assisted living, healthcare monitoring, rehabilitation, physiotherapy, and geriatric care. Conventional methods of HAR use wearable sensors, e.g., acceleration sensors and gyroscopes. However, they are limited by issues such as sensitivity to position, user inconvenience, and potential health risks with long-term use. Optical camera systems that are vision-based provide an alternative that is not intrusive; however, they are susceptible to variations in lighting, intrusions, and privacy issues. The paper uses an optical method of recognizing human domestic activities based on pose estimation and deep learning ensemble models. The skeletal keypoint features proposed in the current methodology are extracted from video data using PoseNet to generate a privacy-preserving representation that captures key motion dynamics without being sensitive to changes in appearance. A total of 30 subjects (15 male and 15 female) were sampled across 2734 activity samples, including nine daily domestic activities. There were six deep learning architectures, namely, the Transformer (Transformer), Long Short-Term Memory (LSTM), Gated Recurrent Unit (GRU), Multilayer Perceptron (MLP), One-Dimensional Convolutional Neural Network (1D CNN), and a hybrid Convolutional Neural Network–Long Short-Term Memory (CNN–LSTM) architecture. The results on the hold-out test set show that the CNN–LSTM architecture achieves an accuracy of 98.78% within our experimental setting. Leave-One-Subject-Out cross-validation further confirms robust generalization across unseen individuals, with CNN–LSTM achieving a mean accuracy of 97.21% ± 1.84% across 30 subjects. The results demonstrate that vision-based pose estimation with deep learning is a useful, precise, and non-intrusive approach to HAR in smart healthcare and home automation systems.

Producción Científica

Muhammad Amjad Raza mail , Nasir Mehmood mail , Hafeez Ur Rehman Siddiqui mail , Adil Ali Saleem mail , Roberto Marcelo Álvarez mail roberto.alvarez@uneatlantico.es, Yini Airet Miró Vera mail yini.miro@uneatlantico.es, Isabel de la Torre Díez mail ,

Raza

<a class="ep_document_link" href="/26722/1/nutrients-18-00257.pdf"><img class="ep_doc_icon" alt="[img]" src="/26722/1.hassmallThumbnailVersion/nutrients-18-00257.pdf" border="0"/></a>

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Innovative Application of Chatbots in Clinical Nutrition Education: The E+DIEting_Lab Experience in University Students

Background/Objectives: The growing integration of Artificial Intelligence (AI) and chatbots in health professional education offers innovative methods to enhance learning and clinical preparedness. This study aimed to evaluate the educational impact and perceptions in university students of Human Nutrition and Dietetics, regarding the utility, usability, and design of the E+DIEting_Lab chatbot platform when implemented in clinical nutrition training. Methods: The platform was piloted from December 2023 to April 2025 involving 475 students from multiple European universities. While all 475 students completed the initial survey, 305 finished the follow-up evaluation, representing a 36% attrition rate. Participants completed surveys before and after interacting with the chatbots, assessing prior experience, knowledge, skills, and attitudes. Data were analyzed using descriptive statistics and independent samples t-tests to compare pre- and post-intervention perceptions. Results: A total of 475 university students completed the initial survey and 305 the final evaluation. Most university students were females (75.4%), with representation from six languages and diverse institutions. Students reported clear perceived learning gains: 79.7% reported updated practical skills in clinical dietetics and communication were updated, 90% felt that new digital tools improved classroom practice, and 73.9% reported enhanced interpersonal skills. Self-rated competence in using chatbots as learning tools increased significantly, with mean knowledge scores rising from 2.32 to 2.66 and skills from 2.39 to 2.79 on a 0–5 Likert scale (p < 0.001 for both). Perceived effectiveness and usefulness of chatbots as self-learning tools remained positive but showed a small decline after use (effectiveness from 3.63 to 3.42; usefulness from 3.63 to 3.45), suggesting that hands-on experience refined, but did not diminish, students’ overall favorable views of the platform. Conclusions: The implementation and pilot evaluation of the E+DIEting_Lab self-learning virtual patient chatbot platform demonstrate that structured digital simulation tools can significantly improve perceived clinical nutrition competences. These findings support chatbot adoption in dietetics curricula and inform future digital education innovations.

Producción Científica

Iñaki Elío Pascual mail inaki.elio@uneatlantico.es, Kilian Tutusaus mail kilian.tutusaus@uneatlantico.es, Imanol Eguren García mail imanol.eguren@uneatlantico.es, Álvaro Lasarte García mail , Arturo Ortega-Mansilla mail arturo.ortega@uneatlantico.es, Thomas Prola mail thomas.prola@uneatlantico.es, Sandra Sumalla Cano mail sandra.sumalla@uneatlantico.es,

Elío Pascual